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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO2
All Species:
4.24
Human Site:
S320
Identified Species:
11.67
UniProt:
Q56NI9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56NI9
NP_001017420.1
601
68307
S320
L
G
E
N
K
T
I
S
P
K
S
T
V
Y
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543224
598
67974
P322
S
P
E
S
I
V
Y
P
I
F
S
V
S
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIB9
592
67255
S329
Y
P
I
F
N
V
S
S
V
N
T
K
R
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508920
682
76075
G373
M
K
Q
T
K
S
S
G
S
D
C
K
T
F
P
Chicken
Gallus gallus
XP_420012
679
73766
S393
H
K
G
S
K
K
A
S
S
N
A
L
V
Y
P
Frog
Xenopus laevis
NP_001089603
640
69941
K352
P
V
P
K
P
S
D
K
K
G
P
T
V
F
P
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
S325
S
S
H
D
E
E
E
S
S
V
Y
P
I
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
E442
E
I
D
D
D
M
E
E
T
E
N
L
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146746
323
35496
V90
G
N
D
E
D
E
K
V
H
R
A
Y
H
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
74.2
N.A.
69
N.A.
N.A.
45.8
37.4
36.7
37.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
84.1
N.A.
80
N.A.
N.A.
60.4
53.4
51.5
53.5
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
13.3
33.3
20
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
40
46.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
21.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
23
23
23
0
12
0
0
12
0
0
0
0
0
% D
% Glu:
12
0
23
12
12
23
23
12
0
12
0
0
0
0
12
% E
% Phe:
0
0
0
12
0
0
0
0
0
12
0
0
0
34
0
% F
% Gly:
12
12
12
0
0
0
0
12
0
12
0
0
0
0
12
% G
% His:
12
0
12
0
0
0
0
0
12
0
0
0
12
0
0
% H
% Ile:
0
12
12
0
12
0
12
0
12
0
0
0
12
0
0
% I
% Lys:
0
23
0
12
34
12
12
12
12
12
0
23
0
23
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
0
0
23
12
0
0
% L
% Met:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
12
0
0
0
0
23
12
0
0
0
0
% N
% Pro:
12
23
12
0
12
0
0
12
12
0
12
12
0
12
45
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
12
% R
% Ser:
23
12
0
23
0
23
23
45
34
0
23
0
12
12
12
% S
% Thr:
0
0
0
12
0
12
0
0
12
0
12
23
12
0
0
% T
% Val:
0
12
0
0
0
23
0
12
12
12
0
12
34
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
12
0
0
0
12
12
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _